The Kansas City Chiefs (12-4 SU, 9-6-1 ATS) haven’t claimed the Super Bowl in almost 50 years. They can end that streak with three more wins, starting this Saturday when they host the Indianapolis Colts (11-6 SU, 9-7-1 ATS) in the Divisional Round. Game time is 4:35 PM ET on NBC; the Chiefs are 5-point favorites with a total of 57.

While the Chiefs have been competitive since hiring Andy Reid as their head coach in 2013, they’re a whole new team this year with Patrick Mahomes II at quarterback. Mahomes led the NFL during the regular season with 50 touchdown passes and an 82.0 QBR, piloting the best offense Kansas City has ever seen – but can their defense hold its end of the bargain?

Andrew Luck will put them to the test on Saturday. After missing the entire 2017 campaign with shoulder issues, Luck found his groove in late October, quarterbacking the Colts to nine wins in their last 10 regular-season games (6-3-1 ATS) and a 21-7 victory over the Houston Texans (–1.5 at home) in the Wild Card round. Unfortunately, safety Mike Mitchell appears doubtful to face the Chiefs after straining his calf in Houston.